The GRAPHIC study

The second phase of GRAPHIC (GRAPHIC2) will use labels produced from the LCBRU portal.

Output from the 'label' module will be:

1 x label with patient name and human readable GRAPHIC ID for pathology form 1 x label with GP details for pathology form 1 x label for serum gel bottle for pathology 1 x label for fluoride / glucose bottle for pathology

1 x label for serum vaccutainer 2 x edta red 1 x citrate green 1 x edta purple for FBC processing

1 x urine sterile container

1 x label for consent form (lab number, ID number, name, DOB) 1 x Physical activity form (lab number, ID number) 1 x Physical examination form (lab number, ID number) 1 x Patient Diary for ABPM (lab number, ID number) 1 x spare for paper version of the questionnaire if necessary

15 labels in total per patient.

Contact for the GRAPHIC study is Jay Gracey.

Thinking now is that we might load the GRAPHIC patients into CiviCRM, use Civi to track invitations etc, and then point the label module to the CiviCRM database to access the patient identities.

Contact with patients for GRAPHIC 2

We have already written to all the families in GRAPHIC 1 (i.e. a letter to each 'mother'). Replies indicate 1,000 willing participants for GRAPHIC 2 - could be isolated individuals, could be families. This was not an 'invitation' but a feasibility study. Now ethics approval has been received, the 1000 need to be invited. At the same time, those mothers who did not reply will get a reminder, asking them to consider participating.

The 1,000 are in an access database (including their GRAPHIC ID numbers). May need some work but could export it into CiviCRM. Activity schedule is really just a one visit, but ABPM might be done on a separate visit.

FBC samples will be processed in the LCB lab, but this will need a specific data acquisition process which Richard is working on. Other blood results will come from pathology system, using the same DWH approach into i2b2 that we use for BRICCS and GENVASC.

GRAPHIC 2 commits us to send a summary to the patient's GP containing their blood results and ABPM data. The blood results will go directly from the pathology department. A pro forma can be sent by the nurse, commenting that the GP should already have received the results, so there is no need to transcribe them.

Device driver installations

Spirometry (CareFusion) software and drivers will need installing on the two laptops AND on desktop machines in the TMF (room one and room three, and OP53) and in BRU2/CRF (room three).

ABPM software will also need to go on the same machines.

Jay will let me know the machine names, so I can log a support call for local admin rights.