GENVASC Collection Protocol: - Initial recruitment samples - 9.8 ml whole blood in Serum Tube (two tubes logged as one merged sample) - DERVIVED: 5 ml Serum - ALIQUOTED: 4 x 1ml aliquots [stored] - 9.8 ml whole blood in EDTA tube (two tubes logged as one merged sample) - DERIVED: 5 ml EDTA Plasma - ALIQUOTED: 4 x 1ml plasma aliquots [stored] - DERIVED: 1000 cells of buffy coat - ALIQUOTED: 500 cells of buffy coat [stored] - DERIVED: DNA 100ug - ALIQUOTED: 4 x 25ug DNA - ALIQUOTED: 500 cells of buffy coat [stored] - DERIVED: DNA 100ug - ALIQUOTED: 4 x 25ug DNA